Weight loss

A Simple Guide to Ozempic, Mounjaro and Wegovy: How They Help with Diabetes and Weight Loss

By Dr. Janine McKay & Hissa A. AlSudairy

  1. Ozempic (semaglutide): This GLP-1 receptor agonist works by increasing insulin release, reducing glucagon levels, and slowing gastric emptying. As a result, it helps lower blood sugar levels and promotes weight loss by reducing appetite and increasing feelings of fullness.
  2. Mounjaro (tirzepatide): This dual agonist targets both GLP-1 and GIP receptors, offering a broader range of effects. By combining the benefits of both incretin hormones, Mounjaro enhances glycemic control and supports more significant weight loss compared to GLP-1 agonists alone.
  3. Wegovy (semaglutide): Similar to Ozempic, Wegovy uses semaglutide but is specifically approved for chronic weight management in individuals with obesity or overweight. It aids in weight loss by curbing appetite and enhancing feelings of satiety.
  1. Diet: A balanced diet rich in whole foods, including fruits, vegetables, lean proteins, and whole grains, supports blood sugar management and weight loss. Avoiding intake of processed foods, sugary beverages/juices, and saturated/trans fats is essential for optimizing the effects of GLP-1 and GIP medications.
  2. Exercise: Regular physical activity enhances insulin sensitivity, aids in weight management, and improves overall cardiovascular and mental health. Aim for at least 150 minutes of moderate-intensity exercise per week, such as brisk walking, swimming, or cycling.
  3. Behavioral Changes: Adopting mindful eating practices, managing stress, and ensuring adequate sleep are integral components of a holistic approach to health. These behavioral changes support the effectiveness of medications and contribute to overall well-being.